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Management of sickle cell priapism with etilefrine.(Statistical Data Included)
Abstract
Intracavernous injections of etilefrine were effective in seven children with acute sickle cell priapism, and stuttering priapism resolved in five children after one to seven months of oral etilefrine. Compared with our previous reports in adults, etilefrine appears to be more effective in childhood.
(Arch Dis Child 200 1;85:52-53)
Keywords: priapism, alpha adrenergic agonist; sickle cell anaemia
Priapism is a painful vaso-occlusive complication of sickle cell anaemia (SCA). Recently, the actuarial probability of young males with SCA experiencing priapism by 20 years of age was estimated at 89%. [1] For some years, treatment of priapism has included the use of [alpha] adrenergic agonists. [2-4] Most published information concerns adults. We aimed to assess the results of this treatment in 11 children with SCA consecutively treated in Lome-Tokin's teaching hospital.
Patients and methods
In 1996, we established a prospective management protocol for outpatient treatment of sickle cell priapism, approved by the ethics commitee of the hospital. Eleven children with SCA, aged 2.5-15 years, and admitted from 1996 to 1999, were …
