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More antioxidants, less fat may curb Alzheimer's. (Diet During Midadult Life).

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| November 01, 2002 | Tucker, Miriam E. | COPYRIGHT 2002 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

STOCKHOLM -- A high-antioxidant, low-fat diet during midadult life may reduce the risk for developing Alzheimer's disease, Grace J. Petot said in a poster presentation at the Eighth International Conference on Alzheimer's Disease and Related Disorders.

Data are now strong enough to recommend a dietary strategy for reducing Alzheimer's disease (AD) risk that includes low fat intake and high consumption of fish and antioxidants, along with vitamin E, folic acid, and vitamins [B.sub.6] and [B.sub.12] supplements, Dr. Robert P. Friedland said in a separate presentation at the conference, sponsored by the Alzheimer's Association.

"These recommendations have not been demonstrated to be effective in a population-based study, but they are safe, inexpensive, and in keeping with public health guidelines," said Dr. Friedland, professor of neurology at Case Western Reserve University, Cleveland. He was a coauthor on Ms. Petot's case-control study of 96 AD patients and 214 controls aged 65 or older.

Controls and surrogates for the patients completed dietary history questionnaires for three age periods: 20-39 years, 40-59 years, and 60-plus years, Ms. Petot said.

Two major dietary patterns were identified. One was labeled "low-antioxidant high-fat," and ...

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