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Common questions posed by pregnant patients. (Is it Safe to dye My hair? Drink Coffee?).
BIG SKY, MONT. -- Be sure to ask about caffeine intake in women with first-trimester pregnancy loss, Dr. Jodi Schucker advised at an ob.gyn. update sponsored by the Geisinger Health System.
Several epidemiologic studies have linked high caffeine intake to increased risk of first-trimester spontaneous abortions involving karyotypically normal fetuses. On the other hand, multiple studies have failed to show any evidence that caffeine consumption is teratogenic, said Dr. Schucker, a perinatologist at Geisinger Medical Center in Danville, Pa.
Moderate caffeine ingestion wasn't linked to adverse effects on gestational age or birth weight in a recent 873-patient Swedish study (Am. J. Epidemiol. 155[5]:429-36, 2002).
Caffeine's safety in pregnancy is one of those questions patients pose to physicians again and again. Other frequent concerns include the safety of artificial sweeteners, chemical hair treatments, and vaccination. Here's Dr. Schucker's take on these subjects:
* Caffeine. Most researchers define moderate caffeine intake as less than 300 mg/day. A 150-cc mug of brewed coffee averages 115 mg Instant coffee contains 60 mg, cola 15 mg, iced tea 39 mg, and hot cocoa just 4 mg.
A dose-response effect between caffeine intake and spontaneous abortion was demonstrated in a case-control study involving 562 Swedes with first-trimester pregnancy loss. Investigators at Stockholm's Karolinska Institute found no increased risk in women who ingested less than 100 mg/day a 1.3-fold elevated risk with 100-299 mg/day, and a 1.4-fold increased risk in women ingesting 300-499 mg/day.
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Source: HighBeam Research, Common questions posed by pregnant patients. (Is it Safe to dye My...