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Stem cell breakthrough. (Science And Environment).(Catherine M. Verfaillie's report on stem cell research in the July 2002 issue of Nature)

The American Enterprise

| October 01, 2002 | Murray, Iain | COPYRIGHT 2002 The American Enterprise, a national magazine of politics, business and culture (TEAmag.com). This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Catherine M. Verfaillie, et al."Pluripotency of Mesenchymal Stem Cells Derived from Adult Marrow," in Nature, July 2002 (nature.org)

Stem cells are "generic" cells that divide to replenish specific cells lost due to injury or routine wear and tear on the body. There are two forms of stem cells. Embryonic stem (ES) cells are the very early cells that change and reproduce to form all the body parts in developing young creatures. Adult stem cells take many forms. There are some in the skin that produce wave after wave of daughter cells to replenish continually flaking off skin. The same goes for blood: Stem cells in bone marrow are capable of creating all different blood cell types throughout a person's life. Embryonic stem cells are very different. Derived from early-stage embryos in the laboratory, they grow rapidly, and can be maintained in their "raw," undifferentiated state. A researcher can take these cells, inject them into a new mouse embryo, and return it to the womb. There, the mouse ES cells are able to contribute to every tissue type of the adult animal. This means that ES cells are totipotent--they can give rise to all types of cells, which is why human ES cells are considered so promising. In theory, their totipotency sets ES cells apart from the sorts of adult stem cells described above, since nobody thought that a blood ...

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Source: HighBeam Research, Stem cell breakthrough. (Science And Environment).(Catherine M....

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