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(From Chemical Business NewsBase: New Scientist UK Edition)
A prime candidate for treating Alzheimer's disease is emerging from an antibiotic, clioquinol, that removes metals from the brain. This lends support to a controversial theory that the accumulation of metals, rather than the formation of insoluble plaques, is responsible for the disease's characteristic mental deterioration. Clioquinol binds to copper and zinc and is sufficiently small to get into the brain. It was last used in the 1970s to treat intestinal infections. Scientists at the Harvard Medical School, the University of Melbourne, and Prana Biotechnology in Melbourne are developing the drug as an …