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Diabetes risk after gestational diabetes rises with DMPA use. (Progestin Increases Insulin Resistance).
ASHLAND, ORE. -- Women with a history of gestational diabetes were significantly more likely to develop subsequent diabetes if they used depot medroxyprogesterone acetate rather than combination oral contraceptives, a University of Arizona study found.
The 5-year cumulative rate of diabetes was in depot medroxyprogesterone acetate (DMPA) users and in users of combination oral contraceptives, for an adjusted relative risk of 1.75 associated with the use of DMPA, Dr. Matthew van der Veen reported at the annual meeting of the Pacific Coast Obstetrical and Gynecological Society.
"I don't think DMPA should be contraindicated in women with a history of gestational diabetes, but I think women and their physicians should be aware of the risks when choosing a contraceptive," he said.
In the current study, 602 nondiabetic women were monitored for up to 12 years following a pregnancy in which gestational diabetes was diagnosed. Contraceptive choices were left up to the participants; 455 chose combination oral contraceptives and 147 chose DMPA.
There were several differences in the two groups of women.
Those who selected combination oral contraceptives weighed less at ...
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Source: HighBeam Research, Diabetes risk after gestational diabetes rises with DMPA use....