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Regular consumption of two alcoholic drinks per day improves insulin sensitivity and reduces fasting insulin in nondiabetic postmenopausal women, Dr. Michael J. Davies reported at the annual meeting of the Endocrine Society.
Fifty-one postmenopausal women not on hormone replacement therapy were assigned to consume 15 g of alcohol per day--equivalent to one drink--for 8 weeks. Everything that participants ate during the study was prepared at the USDA's Beltsville (Md.) Human Nutrition Research Center, where Dr. Davies works.
For another 8 weeks, the study participants consumed 30 g of alcohol per day During a third 8-week period, they consumed no alcohol.
After 8 weeks of consuming 30 g of alcohol per day, the women's mean fasting serum insulin level stood at 33.5 picomoles/L after adjusting for body mass index. This was significantly lower than the mean 39.4 picomoles/L when the patients consumed no alcohol. An index of insulin sensitivity showed a statistically significant 7% increase with consumption of 30 g of alcohol daily.
Women who consumed 30 g of alcohol per day also experienced significantly increased HDL and reduced triglycerides, compared with when they consumed no alcohol.
When women consumed 15 g of alcohol per day, similar but weaker trends were noted in ...