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COPYRIGHT 2002 American Academy of Family Physicians
More than 5 million Americans have had a stroke, and more than 500,000 new strokes occur every year. Sixty percent of survivors suffer residual disability. Stroke is the second leading cause of death and disability in developed countries. Although elevated blood pressure is the leading risk factor for stroke, most strokes occur in patients whose blood pressures are below the range at which therapy is used. Studies show that angiotensin-converting enzyme (ACE) inhibitors have multiple effects on blood vessel walls and other components of vascular integrity, suggesting that these drugs could prevent stroke independent of their ability to lower...
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