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Women who use hormone replacement therapy are at significantly increased risk for dry eye syndrome, said Debra A. Schaumberg, Sc.D., and her associates at Brigham and Women's Hospital in Boston.
The prevalence of clinically diagnosed or self-reported severe dry eye syndrome was 5.9% among women who had never used HRT, 6.7% among women taking combined estrogen and progesterone replacement therapy, and 9.1% among women using estrogen-only replacement therapy, the investigators said (JAMA 286[17]:2114-19, 2001).
Data on dry eye syndrome were collected ...