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Botox may help patients regain bladder control for 6 months. (Off-Label Use).

OB GYN News

| October 15, 2002 | Sullivan, Michele G. | COPYRIGHT 2002 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

ORLANDO, FLA. -- Botulinum toxin A, when injected into the external sphincter or bladder walls, allows some chronically incontinent patients to regain bladder control for up to 6 months, Dr. Michael Chancellor reported at the annual meeting of the American Urological Association.

The injections are useful for patients who have voiding dysfunctions that stem from sphincter spasticity, including those with multiple sclerosis, spinal cord injury stroke, and overactive bladder and interstitial cystitis, said Dr. Chancellor, a urology surgeon m Pittsburgh.

Botulinum toxin A (Botox) can also be injected into the bladder wall to help alleviate some of the pain associated with bladder spasms, he said.

"This is nature's most perfect, poison, but it is also a robust drug that has applications far beyond the cosmetic use for which it is known," Dr. Chancellor said in a press conference describing his 3-year experience in treating lower urinary tract dysfunctions with the neurotoxin.

Dr. Chancellor administered a total 100-200 units of botulinum A toxin (Botox) to each of 53 patients with sphincter spasticity. The toxin was divided into four equal doses and injected in the sphincter's four quadrants. For 22 patients with ...

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Source: HighBeam Research, Botox may help patients regain bladder control for 6 months....

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