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ASHEVILLE, NC. -- Although the literature recommends against treating Trichomonas vaginalis infection and bacterial vaginosis in asymptomatic pregnant women, physicians still face a compelling dilemma in this regard, Dr. Philip Heine said at the annual Southern Obstetric and Gynecologic Seminar.
"Am I really comfortable with this? No, because there are other arguments for treating STDs. They potentially increase the risk for acquisition of other STDs, including HIV and so it makes me very uncomfortable to not treat these infections," he told this newspaper.
The evidence against treating asymptomatic T. vaginalis comes from a study that found an increased rate of preterm delivery among asymptomatic patients treated for T. vaginalis, compared with those on placebo (N. Engl. J. Med. 342[8]:534-40, 2000).
In the treatment group, 19% of the patients were delivered before 37 weeks' gestation, compared with 11% of those in the placebo group, said Dr. Heine, chief of maternal-fetal medicine at Duke University, Durham, N.C.
Studies of preterm delivery in low-risk patients with asymptomatic bacterial vaginosis have found that treatment was not associated with any increased risks or benefits.
Dr. Heine pointed out that physicians need to ...