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Protease inhibitors seem safe during pregnancy. (Review of 233 Women).

OB GYN News

| September 15, 2002 | Zoler, Mitchel L. | COPYRIGHT 2002 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

BARCELONA, SPAIN -- Treatment with a protease inhibitor was generally safe for pregnant women and their infants, based on a retrospective review of 233 pregnant women who received the drug.

Prematurity and low birth weight were not associated with an individual protease inhibitor or with the gestational age when protease-inhibitor treatment began, Dr. Anne B. Morris said while presenting a poster at the 14th International AIDS Conference.

The transmission rate for HIV in this series was 2 infants born infected with HIV out of a total of 231 infants delivered (0.9%). Six infants were stillborn, and HIV status was unknown in three.

The study included all women treated with protease inhibitors at five centers from December 1997 through December 2001.

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