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BARCELONA, SPAIN -- Treatment with a protease inhibitor was generally safe for pregnant women and their infants, based on a retrospective review of 233 pregnant women who received the drug.
Prematurity and low birth weight were not associated with an individual protease inhibitor or with the gestational age when protease-inhibitor treatment began, Dr. Anne B. Morris said while presenting a poster at the 14th International AIDS Conference.
The transmission rate for HIV in this series was 2 infants born infected with HIV out of a total of 231 infants delivered (0.9%). Six infants were stillborn, and HIV status was unknown in three.
The study included all women treated with protease inhibitors at five centers from December 1997 through December 2001.
...Source: HighBeam Research, Protease inhibitors seem safe during pregnancy. (Review of 233 Women).