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Breast-feeding linked to reduced breast ca risk. (Duration and Incidence).
Breast-feeding duration and incidence are both associated with reduced breast cancer risk, results of a large international study suggest.
For every year of breast-feeding, the relative risk of breast cancer decreased by 4.3%, and for every child breast-fed, the relative risk decreased by 3.4%, Dr. Valerie Beral of Radcliffe Infirmary, Oxford, England, and her associates reported (Lancet 360[9328]:187-95, 2002).
Childbearing has long been known to be protective against breast cancer, but the contribution of breast-feeding to the level of that protection has been unclear, the investigators noted.
They compared more than 50,000 women with invasive breast cancer and nearly 97,000 controls. Data were collected from 47 epidemiologic studies of breast-feeding and childbearing patterns in 30 countries.
Compared with parous controls, parous breast cancer patients had a lower incidence of ever having breast-fed (79% vs. 7 1%), a shorter average duration of breast-feeding (15.6 months vs. 9.8 months), and fewer mean births (2.6 vs. 2.2).
The size of the decline in relative risk for breast cancer based on childbearing and breast-feeding duration did not differ significantly between developed and developing countries (or based on age, menopausal status, ethnic origin, parity, or age at first delivery). The higher incidence of breast cancer in ...
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