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Combination therapy with Actos (pioglitazone HCl) shown to improve components of diabetic dyslipidemia.

Asia Africa Intelligence Wire

| April 30, 2004 | COPYRIGHT 2003 Financial Times Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

(From Chemical Business NewsBase - Press Release)

Results of three studies show the oral anti-diabetic agent Actos (pioglitazone HCl), in combination with a sulfonylurea, metformin or insulin, resulted in triglyceride decreases, and high-density lipoprotein (HDL) cholesterol increases that demonstrated statistically significant improvements from baseline. These studies also showed that, in addition to increasing low-density lipoprotein cholesterol particle size, Actos can significantly increase the size and buoyancy of HDL particles. The findings were presented at the 13th Annual Meeting and Clinical Congress of the American Association of Clinical Endocrinologists…

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