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BERLIN -- Women with breast cancer were much less likely than other postmenopausal women to suffer an osteoporosis-related fracture in a large case-control study presented at the 10th World Congress on the Menopause.
The prevalence of an osteoporotic fracture was 6.26% among 3,100 postmenopausal women with breast cancer and 8.81% among 100,000 age-matched controls for an odds ratio of 0.69 in the U.K. study.
The highly significant inverse association "is consistent with the likelihood that breast cancer is associated with high, and osteoporotic fracture with low, estrogen levels," noted Dr. Madge Vickers of the Medical Research Council's clinical trials unit in London.
The government-sponsored study was part of the Women's International Study of Long-Duration Oestrogen After Menopause (WISDOM) trial.
That trial is ...