Does adiposity rebound (AR) occur earlier in children with congenital hypothyroidism (CH)?(Endocrinology and Diabetes)(Brief Article)

Aim: To study the timing of AR and body mass index (BMI) from infancy to late childhood in CH.

Methods: We performed a retrospective study of BMI and timing of AR in children with CH. Mean length/height and BMI were determined at 1, 4, 6, and 10 years. Timing of AR was determined by visual inspection of BMI v age graph plotted for each patient. The proportion of children with CH who reached AR by 37 months and 49 months were compared with two groups of children described in the literature: 889 healthy British children and 68 Scottish children treated for acute lymphoblastic leukaemia (ALL). Correlation of timing of AR with BMI at 10 years, initial severity of …