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The pattern of MRSA in UK hospitals nowadays is very different to that seen a decade or so ago. Then, MRSA was confined mainly to a relatively small number of hospitals in the southeast of England and some of the large provincial conurbations. (1) However, new strains of epidemic MRSA, especially EMRSA-15 and EMRSA-16, have since emerged and spread to become established to some extent in virtually every hospital in the country. (1) Between 1992 and 2002 the proportion of blood culture isolates of Staphylococcus aureus reported by microbiology laboratories to the Communicable Disease Surveillance Centre that were methicillin resistant increased from 3% to 43%. (2) The ...