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Modafinil may reduce residual fatigue, sleepiness. (Adjunctive Depression Therapy).(Brief Article)

Clinical Psychiatry News

| July 01, 2002 | Sherman, Carl | COPYRIGHT 2009 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

PHILADELPHIA -- Modafinil may be a useful adjunctive treatment for depressed patients who have residual symptoms such as fatigue and daytime sleepiness after partial response to antidepressant therapy, Dr. Karl J. Doghramji said at the annual meeting of the American Psychiatric Association.

Patients showed rapid and significant improvements in these symptoms, in a placebo-controlled trial of the wakefulness-promoting agent, said Dr. Doghramji, professor of psychiatry and director of the sleep disorders center at Thomas Jefferson University, Philadelphia.

Fatigue, sleepiness, and such related phenomena as impaired concentration and reduced energy are extremely…

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