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Hepatitis C, HIV connection. (Infectious Diseases).
Mortality rates appear to be increasing among HIV-infected people with concomitant hepatitis C infections, Dr. Douglas T. Dieterich said at an update on viral infections sponsored by the University of British Columbia.
Data from one Boston clinic indicate that deaths due to end-stage liver disease have increased from 10% of HIV-related deaths in 1991 to 50% of such deaths in 2001. Liver disease due to hepatitis C progresses more rapidly in people coinfected with HIV. Further, the liver disease increases the risk of toxicity from antiretroviral therapies.
Of the HIV-infected patients who had concomitant hepatitis C infections and died, 55% had undetectable HIV viral loads and CD4 counts above 200 cells/[micro]L. It appeared that their HIV ...
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