AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.

Staining may indicate invasive breast cancer. (Investigational Procedure).

OB GYN News

| July 01, 2002 | MacReady, Norra | COPYRIGHT 2002 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

SAN FRANCISCO -- In the not too distant future, physicians may be able to identify the patients with early-stage breast cancer who run the highest risk of developing invasive carcinoma and metastases, thanks to a staining test developed at the University of Michigan in Ann Arbor.

The test detects a protein called RhoC, which is produced by invasive, inflammatory breast cancer cells, as well as by certain tumors of the liver, pancreas, and skin. Women who have small breast tumors but high RhoC levels could be candidates for more aggressive early treatment, Dr. Celina Kleer said at the annual meeting of the American Association for Cancer Research.

RhoC is shorthand for RhoC-GTPase, an enzyme normally involved in muscle cell structure and motility. But in tumor cells that express it, RhoC confers the ability to detach and metastasize.

Using 184 breast tissue slides from 164 patients, Dr. Kleer and her colleagues tested a specially developed polyclonal ...

Related articles from newspapers, magazines, journals, and more
Recent findings in breast cancer described by C.M. Heaphy and colleagues.
Newspaper article from: Cancer Weekly September 29, 2009 700+ words
...supporting the notion that invasive carcinomas evolve from or in parallel...published their study in Breast Cancer Research and Treatment...similarity between DCIS and invasive carcinomas. Breast Cancer Research and Treatment...
Research findings from H. Onishi et al update understanding of breast...
Newspaper article from: Cancer Weekly August 11, 2009 700+ words
...surgical treatment for breast cancer and 10 normal volunteers...report (see also Breast Cancer). "All 30 patients...surgical treatment, and breast cancer was proved histopathologically...eight patients had 35 invasive carcinomas, and the remaining...
Data on breast cancer genetics published by researchers at University of...
Newspaper article from: Cancer Weekly August 4, 2009 700+ words
...detailed in 'Unraveling breast cancer heterogeneity through...Surgical Oncology, "Breast cancer diversity is histologically...carcinomas, and invasive carcinomas that may develop...in the course of breast cancer progression. Additionally...
Research reports on breast cancer therapy from University Medical Center,...
Newspaper article from: Cancer Weekly August 4, 2009 700+ words
...13%) for the invasive carcinomas (p=0.0001...25 days for the invasive carcinomas (p=0.0001...Surgery (see also Breast Cancer Therapy). The...Netherlands, Utrecht, Breast Cancer Therapy, Biopsy...
Data from Central Hospital advance knowledge in breast cancer risk factors.
Newspaper article from: Cancer Weekly September 1, 2009 700+ words
...potential,' new data in breast cancer. "We analyzed 301 consecutive...Sweden report (see also Breast Cancer Risk Factors). "One...compared to unifocal invasive carcinomas. Invasive carcinomas with diffuse in situ component...
New breast cancer data have been reported by researchers at University of...
Newspaper article from: Cancer Weekly December 8, 2009 700+ words
...marker for increased breast cancer risk and is associated...report (see also Breast Cancer). "The purpose...for screening of breast cancer was conducted. The...diagnosis of primarily invasive carcinomas in 0.32% of women...
Studies from E. Brautigam and colleagues yield new information about breast...
Newspaper article from: Cancer Weekly October 20, 2009 700+ words
...tumor localization in breast cancer--an unappreciated...patients with medial breast cancer compared to patients...of 1,100 pT1-2 invasive carcinomas of the breast were...colleagues, (see also Breast Cancer Risk Factors...
Use of RF on breast cancer 'feasible and safe,' says study.
Newspaper article from: Medical Device Daily April 8, 2004 700+ words
Use of RF on breast cancer feasible and safe...ablation to treat breast cancer was published in the...to ablate small, invasive carcinomas is feasible and safe...ablation treatment for breast cancer is still a longer...
For more facts and information, see all results

Source: HighBeam Research, Staining may indicate invasive breast cancer. (Investigational...

©2009 Gale, a part of Cengage Learning. All rights reserved.
About us | FAQs | Contact us | Privacy policy | Terms and conditions
Other Gale sites: Encyclopedia.com | HighBeam Research | Acquire Content | Books & Authors | Goliath | MovieRetriever | Smart QandA