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<a href="http://www.accessmylibrary.com/coms2/summary_0286-2106026_ITM" title="Facts and information about Large trial backs use of [MgSO.sub.4] in preeclampsia. (Lower Seizure Rates).">Large trial backs use of [MgSO.sub.4] in preeclampsia. (Lower Seizure Rates).</a>
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Large trial backs use of [MgSO.sub.4] in preeclampsia. (Lower Seizure Rates).
A large randomized, prospective, controlled trial confirms that women with preeclampsia are significantly less likely to have life-threatening seizures if given magnesium sulfate either before or after delivery than if given placebo.
Many American ob.gyns. regularly use magnesium sulfate ([MgSO.sub.4]) despite a lack of empiric evidence, but data from the Magnesium Sulfate for Prevention of Eclampsia (MAGPIE) trial, an international study of more than 10,000 preeclamptic women, give scientific support to the procedure (Lancet 359[9321]:1877-90, 2002).
The women--who had not given birth or were 24 hours or less post partum-- were randomized to either a loading dose of 8 mL magnesium sulfate or placebo, ...
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Source: HighBeam Research, Large trial backs use of [MgSO.sub.4] in preeclampsia. (Lower Seizure...