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Daily observed tuberculosis Tx for 2 weeks works. (Then Twice Weekly Tx for 24 Weeks).(Brief Article)(Statistical Data Included)
Two weeks of directly observed daily therapy, followed by 24 weeks of twice-weekly medication, are effective in treating tuberculosis in children, reported Dr. Fahad S. Al-Dossary and his associates at Baylor College of Medicine in Houston.
And this method can easily be used in an ordinary clinical setting. The number of TB cases among children under age 15 years in the United States declined 39% from 1992 to 1,044 cases in 1999. Most studies of tuberculosis treatment in children have examined daily treatment for 12 months, followed by 4 months of twice-weekly therapy (Pediatr. Infect. Dis. J. 21[2]:91-97, 2002).
In the current observational study, 185 children aged 5 months to 17 years with TB received daily treatment with isoniazid, pyrazinamide, and rifampin every day for 2 weeks, except on weekends. A trained worker from the Houston Tuberculosis Control Division watched the ...