AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Early clinical markers of preeclampsia under study. (Pulse Pressure, Endothelial Function).
HILTON HEAD, S.C. -- Measures of pulse pressure and endothelial function may someday help obstetricians identify patients in the earliest stages of preeclampsia and those who are likely to progress to the most severe forms of the condition, according to the results of two studies.
While it's well known that the preclinical stage of preeclampsia is associated with significant pathologic changes such as increased cardiac output and arterial stiffness very early in pregnancy, there are no clear, easy-to-use clinical markers of these changes, Dr. Rishimani S.N. Adsumelli said at the annual meeting of the Society for Obstetric Anesthesia and Perinatology.
Dr. Adsumelli's theory is that pulse pressure--the difference between systolic and diastolic blood pressures--could spike early in the pregnancies of women destined to develop preeclampsia. Pulse pressure is an indication of central artery dysfunction, and significant, ongoing elevations in pulse pressure could lead to endothelial damage, said Dr. Adsumelli of the State University of New York at Stony Brook.
She and her associates reviewed the charts of 44 women with preeclampsia and 187 matching control women seen between January 1999 and December 2000.
Only healthy primiparous women with singleton pregnancies were included in the analysis.
Even after controlling for other variables, the researchers found that pulse pressure during the first trimester was independently associated with preeclampsia. Women who eventually developed preeclampsia had a mean pulse pressure of 49 mm Hg before 15 weeks' gestation, compared with a mean pressure of 42.4 mm Hg among women who had normal pregnancies.
While that difference is statistically significant, only future research will help determine how clinically significant it is, Dr. Adsumelli added.
- Diastolics Below 80 mm Hg Lower Stroke Risk.(Statistical Data Included)
- Magazine article from: Family Practice News GOLDMAN, ERIK L. April 1, 2000 700+ words
...initial stroke, diastolic pressures over 90 mm Hg confer a significant increase in risk for...to push the diastolic pressure below 80 mm Hg. "The optimal poststroke blood pressure...pressures that have been decreased to below 80 mm Hg," Dr. Friday noted. In that study...
- Hypertension treatment in the elderly needs careful scrutiny: octogenarians may...
- Magazine article from: Heart Advisor Vidt, Donald June 1, 2009 700+ words
...top number) reading of more than 140 mm Hg and a diastolic (lower number) reading of less than 90 mm Hg. It's the most common form of hypertension...blood pressure (SBP) of less than 140 mm Hg and a diastolic blood pressure (DBP) of...
- Systolic target of 135 mm Hg cuts diabetes mortality: deaths reduced by 14%,...
- Magazine article from: Internal Medicine News Zoler, Mitchel L. September 15, 2007 700+ words
...for patients with diabetes at 130/80 mm Hg. But no major trial results have ever...average systolic blood pressure of 135 mm Hg. The treatment also produced a 14% relative...systolic pressure in the control arm was 140 mm Hg. The findings are important because they...
- You Can Lower the Blood Pressure 10 mm Hg with Diet Alone!
- Magazine article from: Internal Medicine Alert February 28, 2001 700+ words
You Can Lower the Blood Pressure 10 mm Hg with Diet Alone! Abstract & Commentary...lower systolic blood pressure more than 10 mm Hg after only 30 days. Source: Sacks FM...reduced the systolic blood pressure by 2.1 mm Hg (P < 0.001) in the control diet...
- Adjust treatment goals in hypertensive seniors: in patients with coronary...
- Magazine article from: Family Practice News Zoler, Mitchel L. April 1, 2007 700+ words
...a blood pressure of less than 120/80 mm Hg had a significantly higher rate of death...maintained at a pressure of 120-139/80-89 mm Hg, Rhonda M. Cooper-DeHoff, Pharm...systolic pressure was kept at 120-139 mm Hg. These findings are noteworthy because...
- High, low BP bad for stroke patients: poor outcomes more likely in those with...
- Magazine article from: Renal & Urology News Schieszer, John July 1, 2006 700+ words
...CAD. The team defined high BP as a MAP of 130 mm Hg or higher and low BP as a MAP of 90 mm Hg or less. The investigators evaluated initial...artery disease. Patients with MAPs above 130 mm Hg and below 90 mm Hg were three times as likely...
- Pulse Pressure Builds Steam as Mortality Predictor.(Brief Article)(Statistical...
- Magazine article from: Family Practice News JANCIN, BRUCE January 1, 2000 700+ words
...both), those with a pulse pressure of 48 mm Hg or less had a 4.4...up. Among men with a pulse pressure of 49 mm Hg or higher, the incidence...both), those with a pulse pressure of more than 55 mm Hg had a 4.4% incidence...
- Pulse Pressure, Death Risk Linked in PD Patients.
- Magazine article from: Renal & Urology News May 1, 2009 700+ words
...University of Toronto. Subjects had a mean pulse pressure of 56.8 mm Hg. Age and diabetes significantly predicted elevated pulse pressure. Each 1 mm Hg increment in pulse pressure was associated with a 2.7% increased...