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DENVER -- Autoimmune thyroiditis may be four times as common in women with polycystic ovary syndrome as it is in women without PCOS, Dr. Roland Gaertner reported at the annual meeting of the Endocrine Society.
The association was so strong in an age-matched control study of 58 women with polycystic ovary syndrome and 106 healthy controls that Dr. Gaertner of the University of Munich recommended routine thyroid function testing for women with PCOS.
The women in the study were defined as having PCOS based on an LH/FSH ratio in excess of 2, elevated plasma testosterone, oligomenorrhea, hypertichosis, and, in most patients, ultrasound evidence of polycystic ovaries.
Thyroid status was assessed in patients and controls by measurements of thyroid autoantibodies, free [T.sub.4] and free [T.sub.3], and ultrasound examinations.
Elevated thyroid peroxidase levels or antithyroglobulin antibody levels in excess of 100 U/mL were present in 10% of controls and in 43% (25) of PCOS patients; 20 of these 25 also had an ...