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Natrecor. (New & Approved: Natrecor * InSync Cardiac Resynchronization Therapy * Topamax).
(nesiritide, Scios Inc.)
A recombinant form of human B-type natriuretic peptide (hBNP) for people with acutely decompensated congestive heart failure (CHF), with shortness of breath at rest or with minimal activity. This is the first new treatment approved for decompensated CHF in more than a decade.
Dosage: A loading IV bolus dose of 2 [micro]g/kg, followed by a continuous infusion at a dose of 0.01 [micro]g/kg.
Special Considerations: In the pivotal trial, the rate of symptomatic hypotension in the first 24 hours was similar with IV nitroglycerin (5% of patients) and Natrecor (4%). The episodes lasted significantly longer in those on Natrecor, which has a relatively long half-life and should be administered in a setting where blood pressure can be closely monitored.
Comment: This form of hBNP produced by the left ...
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- Press release article from: PR Newswire September 13, 2004 700+ words
...the heart. About NATRECOR(R) NATRECOR(R) (nesiritide...the treatment of acutely decompensated congestive heart...clinical trials, NATRECOR(R) caused arteries...in patients with acutely decompensated congestive heart...
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- Newspaper article from: Pharma Marketletter April 2, 2007 700+ words
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- Scios Announces International Outcomes Trial of NATRECOR(R) (nesiritide).
- Press release article from: PR Newswire June 1, 2006 700+ words
...profile of NATRECOR(R) in patients with acutely decompensated heart failure...efficacy of NATRECOR(R) as a treatment for acutely decompensated heart failure...patients with acutely decompensated heart failure." About NATRECOR(R) (nesiritide
- Scios Announces FDA Approval of Natrecor.
- Press release article from: PR Newswire August 13, 2001 700+ words
...FDA) to market Natrecor(R) (nesiritide...patients with acutely decompensated congestive heart...approval allows Natrecor to be used in...patients with acutely decompensated congestive heart...to learn about Natrecor, should enable...this market." Acutely ...
- Scios Submits Interim Report to FDA on NATRECOR(R)(nesiritide) PROACTION Trial.
- Press release article from: PR Newswire January 3, 2006 700+ words
...safety of NATRECOR(R) as...patients with acutely decompensated heart failure...Study of Acutely Decompensated Congestive...Outpatients with NATRECOR(R...the use of NATRECOR(R) as a treatment for acutely decompensated heart failure...
- Scios Announces Publication in Journal of the American Medical Association...
- Press release article from: PR Newswire March 26, 2002 700+ words
...flagship product, Natrecor(R) (nesiritide...treatment of acutely decompensated congestive heart...suggest that Natrecor should be used...treatment for acutely decompensated CHF," said...treatment of acutely decompensated heart failure...intravenously, Natrecor is ...
- Study of Safety and Tolerability of Outpatient IV Infusions of NATRECOR(R)...
- Press release article from: PR Newswire September 1, 2004 700+ words
...symptoms. About NATRECOR NATRECOR(R) (nesiritide...the treatment of acutely decompensated congestive heart...clinical trials, NATRECOR caused arteries...in patients with acutely decompensated congestive heart...
Source: HighBeam Research, Natrecor. (New & Approved: Natrecor * InSync Cardiac...