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Insulin Sensitizers and Weight. (Diabetes).

OB GYN News

| October 15, 2001 | Kubetin, Sally Koch | COPYRIGHT 2001 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

The combination of rosiglitazone (Avandia) and an amylose-free diet results in marked and sustained weight loss in non-diabetic hyperinsulinemic obese patients, Dr. Ritchie C. Shoemaker reported at the annual meeting of the Endocrine Society.

Results of a 40-patient, 12-week, open-label pilot study of rosiglitazone and an amylose-free diet were impressive. In the 30 patients who were compliant with the amylose-free diet, the average weight loss was 1.5 pounds per week in women and 1.7 pounds per week in men.

LDL cholesterol levels dropped by 10% and HDL cholesterol levels rose by 4.6%. Both men and women averaged a 1.6-inch decrease in waist circumference, said Dr. Shoemaker of Edward W. McCready Hospital, Crisfield, Md.

Moreover, these patients--all of whom had previously failed to lose weight in ...

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