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Cervical Manipulations Linked to Perinatal Sepsis: Consider GBS-specific chemoprophylaxis. (Eight Case Reports).

OB GYN News

| October 15, 2001 | DeMott, Kathryn | COPYRIGHT 2001 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

QUEBEC CITY -- Obstetricians may want to hold off on performing cervical manipulation or membrane stripping to hasten labor in women with cervical/vaginal infection or colonization with pathogens, Dr. Carol Stamm reported at the annual meeting of the Infectious Diseases Society for Obstetrics and Gynecology.

In a series of eight case reports, Dr. Stamm of the University of Colorado, Denver, described how cervical manipulation or membrane stripping preceded perinatal sepsis and even one instance of stillbirth caused by invasive group B streptococcus (GBS) as well as other pathogens.

In each case, the salient features were the same: Each woman had a history of term gestation in a previously healthy pregnancy. All had elective or nonurgently indicated promotion of labor, digital cervical manipulation, and rapid labor with placental findings of histologically severe intrauterine infection or funisitis, half the time in the absence of classical clinical criteria of chorioamnionitis.

One patient gave birth to a stillborn ...

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