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Certain Types of Fibroids Impact IVF Outcomes.
ASHEVILLE, N.C. -- Uterine leiomyoma are widely believed to have an adverse effect on reproductive outcome, and data are increasingly revealing which types of these fibroids are worth treating, Dr. Stephen W Sawin said at the annual Southern Obstetric and Gynecologic Seminar.
In vitro fertilization data in particular have provided valuable information about fibroids. Some of these data showed that while there is no overall difference in pregnancy outcome between women with or without fibroids, a difference emerges when the types of fibroids are considered independently.
When submucosal and intramural fibroids--as opposed to subserosal fibroids--were present, the success rate with in vitro fertilization was significantly decreased, said Dr. Sawin of the Center for Applied Reproductive Science in Asheville.
These findings were more pronounced when the fibroids distorted the uterine cavity. This makes sense, because it has been shown that a distorted cavity is less receptive to implantation. The enlargement of the uterus due to large fibroids may also be a mechanism by which fibroids can cause infertility, because enlargement can displace the cervix and obstruct the patient's uterine cavity, Dr. Sawin noted.
Miscarriage is also ...
- Uterine Fibroids
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- Newspaper article from: SouthtownStar (Chicago, IL) July 21, 2009 700+ words
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