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<a href="http://www.accessmylibrary.com/coms2/summary_0286-2024549_ITM" title="Facts and information about OCs Don't Reduce Ca Risk in Those with BRCA Mutations.">OCs Don't Reduce Ca Risk in Those with BRCA Mutations.</a>
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OCs Don't Reduce Ca Risk in Those with BRCA Mutations.
Use of oral contraceptives may not protect against ovarian cancer in women with a mutation in the BRCA1 or BRCA2 gene, said Dr. Baruch Modan of the Chaim Sheba Medical Center, Tel-Hashomer, Israel, and colleagues.
Given the increased risk of breast cancer associated with the BRCA1 and BRCA2 mutations, birth control pills should not be prescribed to these women solely for ovarian cancer prevention, the investigators said (N. Engl. J. Med. 345[4]:235-40, 2001).
In a study of 840 Jewish women with ovarian cancer, 240 had the BRCA1 or BRCA2 mutation: The odds ratios for ovarian cancer in these women were 1.14 for those ...
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Source: HighBeam Research, OCs Don't Reduce Ca Risk in Those with BRCA Mutations.