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Combined low dose aspirin and ACE inhibitor treatment is not harmful.(Ischaemic Heart Disease)(Brief Article)

Heart

| November 01, 2003 | Malik, Iqbal | COPYRIGHT 2003 British Medical Association. (Hide copyright information)Copyright

* In patients on angiotensin converting enzyme (ACE) inhibitors for heart failure, treatment included no aspirin in 235 (group 1), a low dose ([less than or equal to] 160 mg) in 45 (group 2), and a high dose ([greater than or equal to] 325 mg) in 64 (group 3). During a mean follow up of 37.6 months, there were 84 (36%) deaths in group 1, 15 (33%) in group 2, and 35 (55%) in group 3. Survival was similar in groups 1 and 2, and significantly (p = 0.009) worse in group 3 compared with groups 1 and 2. After adjusting for potential confounding factors (including treatment, cause of heart disease, age, …

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