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"Not playing is not an option," say TV and magazine ads for Tylenol 8 Hour, a newly launched extended-release pain reliever. The ads show twenty-somethings running, rock climbing, kickboxing, and playing basketball so hard that they hurt.
Despite the marketing aimed at a youthful crowd, Tylenol 8 Hour caplets contain the same 650 milligrams of acetaminophen, at the same suggested retail price, as Tylenol Arthritis. Both products relieve pain. But unlike other pain relievers, acetaminophen can't block the inflammation that underlies aching muscles and joints. So how good is it? Maybe good enough.
The role of inflammation in musculoskeletal injuries is debatable. Some research suggests that it may actually aid in the healing process. The standard strategy to reduce swelling from injury still involves applying ice, but that may not affect the underlying inflammation.
Over-the-counter drugs that target inflammation include four NSAIDs, or nonsteroidal anti-inflammatory drugs: aspirin, ibuprofen (Advil, Motrin), ketoprofen (Orudis KT), and naproxen (Aleve). But the amount of inflammation reduced by the OTC drugs at standard OTC doses is ...