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Some women may be allergic to hormones.(Gynecology)

OB GYN News

| May 01, 2006 | Bell, John R. | COPYRIGHT 2006 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

The hormones progesterone and estrogen might provoke allergic antibody reactions in some women, which might in turn help explain various menstrual disorders, according to a prospective study.

Dr. Russell R. Roby and colleagues from the Roby Institute in Austin, Tex., found increased reactions to both hormones, compared with women who served as controls, in patients with menstruation-related symptoms (Am. J. Reprod. Immunol. 2006;55:307-13).

"Our data presented in this paper are the first to show the presence of IgM and IgE against different steroid hormones," the investigators wrote.

They noted that acne, asthma, epilepsy, allergic rhinitis, and several other disorders have been linked with menstrual cycle influences.

Their report "suggests the possibility of hormone allergy," they wrote, citing earlier studies linking hormone reactions to endocrine disorders and periodic rashes.

The investigators sampled the blood of 270 patients from their clinic who reported a ...

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