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Young black women at risk for aggressive breast tumors.(Gynecology)
WASHINGTON -- Aggressive breast tumors, known as "triple negatives," are significantly more common among black women--especially younger women--than in white women, reported Mary Jo B. Lund, Ph.D., at the annual meeting of the American Association for Cancer Research.
Tumors that test negative for three biomarkers--estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptor 2 (HER2)--are not only more aggressive than are other subtypes of breast cancer, but they can't be treated effectively with tamoxifen or trastuzumab, said Dr. Lund of Emory University in Atlanta.
Dr. Lund and her colleagues evaluated the potential racial differences in the incidence of triple-negative tumors in a group of 117 black women and 362 white women aged 20-54 years. The women had been diagnosed with breast cancer between 1990 and 1992 and were enrolled in a population-based, case-control breast cancer study in the Atlanta area.
The overall incidence of triple-negative tumors was 29.5%, but the tumors were significantly more common among black women, compared with ...
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- Newspaper article from: New Haven Register Abram Katz September 17, 2007 700+ words
...proportion of breast cancer in black women is what Harris calls "triple...United States, 39 percent of black women had estrogen-negative tumors, compared to 22 percent of white patients. Black women were diagnosed at an average...
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- Magazine article from: The Nation's Health Arias, Donya C. November 1, 2007 700+ words
...7 percent of black women. But for women...estrogen receptor-negative tumors were significantly more frequent in black women at every stage...nine percent of black women had estrogen receptor-negative tumors--associated...
Source: HighBeam Research, Young black women at risk for aggressive breast tumors.(Gynecology)