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Proton pump inhibitors and reduced testosterone levels.(Safety and Efficacy Issues)
Netherlands -- Prior to 30 June 2005, the Pharmacovigilance Centre, Lareb, received 28 reports of gynaecomastia associated with the use of proton pump inhibitors (PPIs), including omeprazole, lansoprazole, pantoprazole, esomeprazole and rabeprazole; in most reports there was a latency period of several weeks to months from start of treatment, and all reports were in men. In addition, Lareb has also received several reports of impotence, erectile …
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