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ANAHEIM, CALIF. -- Long-term daily supplementation with 1,200 mg elemental calcium protects against the development of adenomas and hyperplastic polyps, John A. Baron, M.D., reported at the annual meeting of the American Association for Cancer Research.
For up to 5 years after the end of a randomized, placebo-controlled clinical trial, patients who had received calcium supplementation had a 35% reduction in the risk of adenomas and a 41% reduction in the risk of hyperplastic polyps, said Dr. Baron of Dartmouth Medical School, Lebanon, N.H.
But it's still too soon to recommend calcium supplementation to all patients, Dr. Baron said in a press briefing.
"Personally I believe that calcium does reduce the risk of adenomas very clearly and probably reduces the risk of cancer itself as well," he said. "There's one issue that needs to be resolved before calcium can be strongly recommended more generally, and that is that some people believe that calcium supplements may increase the risk of prostate cancer.
"I personally would shy away from making broad recommendations because of this issue," he continued. "For targeted recommendations for women I think you could say that calcium is very likely to be effective and very unlikely to have significant toxicity, with the proviso that you'll probably need to take it for a long time before you see an effect on colorectal cancer."
The original study randomized ...
Source: HighBeam Research, Calcium gives 5 years of colon polyp protection.(Clinical Rounds)