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Severe genital mutilation associated with infertility.(News)
Severe female genital mutilation was associated with primary infertility in a case-control study of 278 women, investigators reported.
Overall, the 99 study participants with primary infertility were significantly more likely to have experienced severe genital mutilation involving the labia majora, compared with 179 controls who were pregnant for the first time (odds ratio 4.69). The researchers controlled for factors including severity of mutilation, socioeconomic status, and seropositivity for Neisseria gonorrhoeae or Chlamydia trachomatis.
Other causes of infertility, such as hormonal factors, prior abdominal surgery, and male infertility, were ruled out before the women were included in the study. Participants were aged 35 years or younger, wrote Lars Almroth, M.D., of the Karolinska Institutet, Stockholm, and his colleagues (Lancet 2005;366:385-91).
Laparoscopy revealed 48 of the infertile women had adnexal pathology that suggested prior inflammation. Of these, 30 women showed bilateral tubal blockage, and 18 showed unilateral tubal blockage.
All but 2 of the infertile women had undergone some form of genital mutilation, and 91 (92%) met the World Health Organization criteria for type III mutilation, ...
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Source: HighBeam Research, Severe genital mutilation associated with infertility.(News)