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Pain expectations linked to pain perception.(research)(Brief article)(Statistical data)

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| October 01, 2005 | Sullivan, Michele G. | COPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Decreased expectation of pain diminishes pain perception by 28%--more than a shot of morphine.

Not only do people who expect less pain report feeling less pain, but their brains respond similarly, with functional MRI (fMRI) showing less activation of pain-related areas, according to Tetsuo Koyama, M.D., Ph.D., and colleagues at Wake Forest University, Winston-Salem, N.C.

The team trained 10 healthy volunteers (aged 26-46 years) to associate tones of different durations with increasingly painful heat stimulation. (Proc. Natl. Acad. Sci. 2005;102:12950-5).

Subjects then underwent 30 trials that were monitored with fMRI. About a third of the time, the ...

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