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First-trimester bleeding in ART tied to poor prognosis.(News)
PRAGUE -- First-trimester bleeding in a singleton pregnancy conceived through assisted reproductive technologies carries a poor obstetric prognosis even when it does not spontaneously abort, reported Dr. Eva Verschueren of University Hospital in Ghent, Belgium.
Moreover, the risk of adverse obstetric outcomes increases with the number of embryos that were initially transferred, she said at the annual meeting of the European Society of Human Reproduction and Embryology.
Bleeding in the first trimester is seen more frequently in pregnancies conceived through assisted reproductive technologies (ART), compared with spontaneously conceived pregnancies.
Several studies have suggested an incidence of 29%-36% in ART pregnancies, compared with 20% in spontaneous pregnancies.
Other researchers have suggested that the bleeding may result from poor implantation or may be caused by a "vanishing twin"--the intrauterine demise of any additional embryos.
Since vanishing twins have been shown by other investigators to be detrimental to the surviving fetus, "our results are yet another argument for elective single embryo transfer," she said. "It is very important that single embryo transfer be used, not just to reduce the risk of multiple pregnancies but also to improve obstetric and neonatal outcomes. Not only for fewer twins ...
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