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Celecoxib approved for AS despite cardiovascular risk.(Clinical Rounds)
Celecoxib, the only cyclooxygenase-2 inhibitor left on the U.S. market, has won an additional approval from the Food and Drug Administration--but, as expected, the drug also received a black box warning on the increased risk of cardiovascular events.
The Pfizer Inc. drug was approved for ankylosing spondylitis (AS), a connective tissue disorder causing inflammation of the spine and large joints that affects about 400,000 Americans, primarily between the ages of 20 and 40 years.
The new warning, a result of an FDA advisory committee's recommendations in February, says that celecoxib (Celebrex) may increase the risk of "thrombotic events, myocardial infarction,…
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Source: HighBeam Research, Celecoxib approved for AS despite cardiovascular risk.(Clinical...
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