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Humble Aquarium Fish May Hold Key to New Therapies for Birth Defects.
Byline: Vanderbilt University
NASHVILLE, Tenn., Aug. 8 (AScribe Newswire) -- A humble aquarium fish may hold the key to finding therapies capable of preventing the structural birth defects that account for one out of three infant deaths in the United States today.
That is one of the implications of a new study published online August 8 in the journal Cell Metabolism. The paper describes a number of striking parallels between a rare but fatal human birth defect called Menkes disease and a lethal mutation in a small tropical fish called the zebrafish that has become an important animal model for studying early development.
Zebrafish are easy and inexpensive to raise and lay eggs that are transparent and develop outside the body. Much of the zebrafish genome has been sequenced, allowing researchers to identify human versions of zebrafish genes and vice versa. These qualities make the zebrafish exceptionally handy in studying the complex relationship between genes and nutrition during development, a puzzle that has stood in the way of developing effective treatments for birth defects. …
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Source: HighBeam Research, Humble Aquarium Fish May Hold Key to New Therapies for Birth Defects.
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