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The role of infection.(MASTER CLASS)
Dr. E. Albert Reece: How important is infection as a mechanism of disease in premature labor?
Dr. Roberto Romero: Intrauterine and systemic infections are a leading cause of spontaneous preterm labor and delivery. Indeed, infections and inflammation are the only mechanisms of disease for which a clear causal link with prematurity has been established. Moreover, a clear molecular pathophysiology has been described.
EAR: How frequent is intrauterine infection in spontaneous preterm birth?
RR: It has been estimated that one of every four preterm births occurs to mothers with intraamniotic infection (defined as a positive amniotic fluid culture for ...
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