AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.

Low-dose estrogens effective for hot flashes.(Gynecology)

OB GYN News

| July 01, 2006 | Schneider, Mary Ellen | COPYRIGHT 2006 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

WASHINGTON -- A 0.45-mg daily dose of synthetic conjugated estrogens-A improves moderate to severe menopausal vasomotor symptoms, compared with placebo, according to data presented at the annual meeting of the American College of Obstetricians and Gynecologists.

The results indicate that postmenopausal women who start estrogen therapy at a low dose may be able to gain the efficacy of higher-dose treatments while having minimal side effects, Dr. James A. Simon of George Washington University in Washington and Dr. Sam S. Miller of the SAM Clinical Research Center in San Antonio wrote in a poster presented at the ACOG meeting.

At week 12 of therapy, nearly 38% of patients taking synthetic conjugated estrogens-A (SCE-A) reported no moderate to severe vasomotor symptoms vs. 7.8% of patients taking placebo, according to the researchers. In addition, the 0.45-mg daily dose of SCE-A reduced the mean weekly frequency of moderate to severe vasomotor symptoms by 67.8 from a baseline of 95.9 at 12 weeks, compared with a mean drop of 42.9 among placebo patients from the same baseline score.

The multicenter, double-blind trial included postmenopausal women, with or without a uterus, who had experienced at least 60 moderate to severe vasomotor symptoms per week. A total of 104 patients were randomized to receive either the 0.45-mg dose of SCE-A or placebo daily for 12 ...

Related articles from newspapers, magazines, journals, and more
Study Data Results Showed Desvenlafaxine Significantly Reduced Moderate to...
Press release article from: PR Newswire October 15, 2007 700+ words
...reduction in moderate to severe vasomotor symptoms (VMS) (hot flashes...women with moderate to severe vasomotor symptoms associated with menopause...treatment of moderate to severe vasomotor symptoms associated with menopause...
Angeliq.(combined hormone therapy for moderate to severe vasomotor symptoms and...
Magazine article from: Internal Medicine News Mechcatie, Elizabeth November 15, 2005 700+ words
Angeliq (drospirenone and estradiol, Berlex Inc.) A combined hormone therapy (HT) for moderate to severe vasomotor symptoms and moderate to severe symptoms of vulvar and vaginal atrophy associated with menopause in women with a uterus...
Wyeth Receives Approvable Letter from FDA for PRISTIQ for the Treatment of...
Press release article from: PR Newswire July 24, 2007 700+ words
...under review as a treatment for moderate-to-severe vasomotor symptoms (hot flashes and night sweats) associated with...as a potential treatment for moderate-to-severe vasomotor symptoms associated with menopause," says Gary L. Stiles...
Novavax, Inc. Comments on Estrogen-Alone Arm of Women's Health Initiative...
Press release article from: PR Newswire March 8, 2004 700+ words
...estrogen for the short-term relief of moderate to severe vasomotor symptoms, the same indications for which ESTRASORB is...is approved for the reduction of moderate to severe vasomotor symptoms, commonly known as hot flashes," commented...
Pivotal Study Results Show New, Plant-Derived Conjugated Estrogen Tablet to be...
Press release article from: PR Newswire October 3, 2002 700+ words
...treatment of moderate to severe vasomotor symptoms associated with menopause...menopausal women suffer from vasomotor symptoms, such as hot flushes...contributes to the relief of vasomotor symptoms. The company's proprietary...
Barr's Cenestin(R) 0.45 mg Tablets Approved; Lowest Cenestin Dose Approved for...
Press release article from: PR Newswire February 6, 2004 700+ words
...dose approved for the treatment of moderate to severe vasomotor symptoms associated with menopause. Cenestin competes...the lowest strength of Cenestin approved for vasomotor symptoms," said Bruce L. Downey, Barr's Chairman...
Study Results Presented at ASRM Show New, Plant-Derived Conjugated Estrogen...
Press release article from: PR Newswire October 14, 2002 700+ words
...treatment of moderate to severe vasomotor symptoms associated with menopause...menopausal women suffer from vasomotor symptoms, such as hot flushes...contributes to the relief of vasomotor symptoms. "Women want to be in...
Lowest Cenestin dose approved for vasomotor symptoms.
News wire article from: Asia Africa Intelligence Wire February 6, 2004 700+ words
...available in the Cenestin product line, is the lowest Cenestin dose approved for the treatment of moderate to severe vasomotor symptoms associated with menopause. Cenestin competes in the Hormone Therapy (HT) market and provides women who choose...
FDA approves once-weekly hormone patch: vasomotor symptoms.(Women's Health)
Magazine article from: Family Practice News Foley, Kevin January 15, 2004 700+ words
...approved the Climara Pro transdermal patch--the first once-a-week, combined hormone therapy for moderate to severe vasomotor symptoms associated with menopause. "Patients appreciate the convenience of a once-a-week patch--it's a great...
Barr's Cenestin(R) 0.45 mg Tablets Available in Pharmacies; Lowest Cenestin...
Press release article from: PR Newswire May 4, 2004 700+ words
...line to five. The 0.45 mg strength is the lowest Cenestin dose approved for the treatment of moderate to severe vasomotor symptoms associated with menopause. Cenestin competes in the Hormone Therapy (HT) market and provides women who chose...
For more facts and information, see all results

Source: HighBeam Research, Low-dose estrogens effective for hot flashes.(Gynecology)

©2009 Gale, a part of Cengage Learning. All rights reserved.
About us | FAQs | Contact us | Privacy policy | Terms and conditions
Other Gale sites: Encyclopedia.com | HighBeam Research | Acquire Content | Books & Authors | Goliath | MovieRetriever | Smart QandA