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Dietary flavonoids may cut breast, ovarian cancer risk.(Gynecology)

OB GYN News

| July 01, 2006 | Splete, Heidi | COPYRIGHT 2006 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

WASHINGTON -- Postmenopausal women who consumed higher amounts of the types of flavonoids found in tea and strawberries showed a decreased risk of breast cancer, according to data presented at the annual meeting of the American Association for Cancer Research.

Breast cancer risk was significantly reduced among postmenopausal women in the highest quintile of dietary flavonol intake compared with the lowest quintile, reported Brian Fink of the University of North Carolina, Chapel Hill, who analyzed data on 1,508 women who had breast cancer and 1,556 controls in the Long Island Women's Health Study. However, no reductions in breast cancer risk were observed among premenopausal women, he noted.

The population-based study included women aged 20-98 years in Nassau and Suffolk counties on Long Island in New York, and was conducted between Aug. 1, 1996, and July 31, 1997. The women answered questions about their reproductive histories, environment, occupations, and lifestyles, including dietary intake, during the past year.

When the flavonoids were broken down into specific types, the significant reduction in breast cancer risk applied to flavones, flavan-3-ols, and lignans only; it did not apply to flavanones, isoflavones, or anthocyanadins. Tea provided the main source of beneficial flavonoids in the women's diets, but strawberries and apples were among the other often-consumed sources.

In another study presented at the meeting, women who consumed kaempferol, a flavonoid found in tea, broccoli, and kale, ...

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