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Pregnancy as 'stress test' could predict future CV health risks.(Obstetrics)

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| July 01, 2006 | Johnson, Kate | COPYRIGHT 2006 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

TORONTO -- Pregnancy could be viewed as a type of cardiovascular "stress test" that could uncover previously silent risk factors for future cardiovascular problems, according to Carl H. Hubel, Ph.D.

"Studying women during pregnancy may facilitate the identification of cardiovascular risk and offer an opportunity for early intervention to decrease their likelihood of developing problems later in life," said Dr. Hubel of Magee Women's Research Institute in Pittsburgh.

Speaking at the annual meeting of the Society for Gynecologic Investigation, Dr. Hubel outlined his own work and that of other researchers that both show that preeclampsia and other complications relating to placental insufficiency such as low birth weight and preterm delivery are associated with an increased risk of cardiovascular events up to 30 years later.

"Metabolic factors predisposing to endothelial dysfunction such as insulin resistance, dyslipidemia, and inflammation may also predispose to preeclampsia and may later manifest as cardiovascular disease," he said, suggesting that endothelial repair is a potential target on the horizon. "Surveillance of cardiovascular risk factors during pregnancy per se may help to identify additional subsets of women who would benefit from early and aggressive risk factor modification post ...

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Source: HighBeam Research, Pregnancy as 'stress test' could predict future CV health...

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