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COPYRIGHT 2006 International Medical News Group
ATLANTA -- The low-molecular-weight heparin enoxaparin was more effective than unfractionated heparin as an adjunct to fibrinolytic therapy in patients with an acute myocardial infarction in a study with more than 20,000 patients.
But enoxaparin's downside was a significant increase in the rate of major bleeding events, which rose from 1.4% in the unfractionated heparin (UFH) group to 2.1% in the enoxaparin group, a 50% relative increase, Dr. Elliott M. Antman reported at the annual meeting of the American College of Cardiology.
The increased bleeding risk with enoxaparin was, nonetheless, a substantial improvement...
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