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Study finds lower suicide rates not due to antidepressant use.(Clinical Rounds)

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| July 01, 2005 | Jancin, Bruce | COPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

BROOMFIELD, COLO. -- The steep rise in antidepressant prescribing over the last several decades and the temporally associated decline in suicide rates in many Western countries are not causally related, Annette Erlangsen, Ph.D., said at the annual conference of the American Association of Suicidology.

Her 5-year study of the entire older population of Denmark--with accompanying data on individual prescriptions filled for antidepressants--showed most of the drop in the Danish suicide rate in the follow-up period involved the 96% not on an antidepressant.

"These findings do not provide information on whether SSR Is [selective serotonin reuptake inhibitors] or other types of antidepressants prevent suicides on an individual level. Nevertheless, our results show that the increased use of SSRIs has not had an impact on the change in the total suicide rate during the second part of life. SSRIs have not worked as a prevention strategy on a universal level," said Dr. Erlangsen of Pennsylvania State University, University Park.

She presented a 5-year follow-up covering the years 1996-2000 involving all of the nearly 2.5 million Danes aged 50 years or older. She restricted her study, which was based upon Danish national health registry data, to older Danes because suicide rates are highest in seniors, who also consume proportionately ...

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