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Older mothers may have special fertility genes.(Gynecology)

OB GYN News

| September 01, 2005 | Johnson, Kate | COPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

COPENHAGEN -- Women who give birth after age 45 may have a special set of genes that makes them more fertile than average women, according to Israeli researchers.

"These women are models for us to learn about fertility," Neri Laufer, M.D., said at the annual meeting of the European Society of Human Reproduction and Embryology.

Dr. Laufer of Hadassah University Medical Center, Jerusalem, outlined his work with more than 200 Ashkenazi Jewish women who had conceived spontaneously after the age of 45 (Fertil. Steril. 2004;81:1328-32).

"More than 80% of these women have six children or more and a low miscarriage rate," he said.

Genetic profiling performed on eight of these women identified a clustering of genes that decreases apoptosis and increases DNA repair. The genes were not found in a control group of six women of the same age whose ...

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