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Vaginal delivery after laparoscopic myomectomy can be accomplished safely without uterine rupture by using management protocols that are similar to those used for vaginal birth after cesarean section, reported Jun Kumakiri, M.D., and his associates at Juntendo University, Tokyo.
In a study of 108 women who wanted to become pregnant after undergoing laparoscopic myomectomy (LM) and were followed for at least 6 months, 40 spontaneous pregnancies and 7 pregnancies by assisted-reproductive technology occurred in 40 women over a 4-year period.
Using Cox regression analysis, the investigators found that pregnancy after LM was positively associated with the diameter of the largest myoma (odds ratio [OR] 1.06) and negatively associated with the patient's age (OR 0.88) and with the number of enucleated myomas (OR 1.17).
A total of 32 deliveries occurred after LM. Of these, vaginal birth was attempted in 23, resulting in 19 (83%) successful vaginal births, with all but one occurring after 37 weeks' gestation. Attempted vaginal birth after LM was unsuccessful in four patients (J. Minim. Invasive ...