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Mothers' folate levels linked to birth weight.(Obstetrics)
Maternal folate status is an important predictor of infant birth weight, a prospective study has shown.
In a cohort of nearly 1,000 expectant mothers, those with lower levels of erythrocyte red blood cell (RBC) folate in early pregnancy were significantly more likely to have low-birth-weight babies, according to Caroline Relton, M.D., and her associates at the University of Newcastle upon Tyne (England).
The researchers investigated the relationship between maternal and newborn RBC folate status, vitamin [B.sub.12] status, maternal smoking, age, parity, and infant birth rate in 998 pregnant mothers receiving prenatal care at a hospital in northwest England and their newborns. Blood samples were collected from mothers during their first routine prenatal appointment and from the newborns' umbilical cords at birth (Br. J. Nutr. 2005;93:593-9).
In a multivariate analysis, maternal folate status was the only significant determinant of birth weight. Each standard deviation increase in maternal folic acid level was associated with a 14% weight increase in birth weight z score.
Univariate linear regression analysis associated smoking with a significant decrease in birth weight; however, multivariate analysis showed a dramatically reduced, nonsignificant influence, suggesting that smoking and ...
- Maternal folate deficiency at end of gestation associated with premature birth.
- Magazine article from: Women's Health Weekly September 2, 2004 700+ words
...Marti-Carvajal and coauthors published their findings in Archivos LatinoAmericanos de Nutricion (Prematurity and maternal folate deficiency: Anemia during pregnancy study group results in Valencia, Venezuela. Arch LatinoAm Nutr, 2004;54(1...
- Fetal mouse brain cells self-destruct when maternal folate levels are deficient.
- Newspaper article from: Blood Weekly March 11, 2004 700+ words
2004 MAR 11 - (NewsRx.com & NewsRx.net) -- Fetal mouse brain cells self-destruct when maternal folate levels are deficient. According to recent research from the United States, "in mice and rats, maternal dietary choline intake...
- Research results from Rowett Research Institute update knowledge of birth...
- Newspaper article from: Blood Weekly May 21, 2009 700+ words
...Nutrition, "In humans poor maternal folate status is associated with a decrease in infant birth weight. As low birth weight increases the risk of cardiovascular...Research Institute (see also Birth Weight). The researchers concluded...
- Low birth weight and residential proximity to PCB-contaminated waste...
- Magazine article from: Environmental Health Perspectives Baibergenova, Akerke Kudyakov, Rustam Zdeb, Michael Carpenter, David O. August 1, 2003 700+ words
...of giving birth to an infant with low birth weight (< 2,500 g), and that this...increased risk of giving birth to a low-birth-weight baby. We used the birth registry of...5% of the 945,077 births. The birth weight in the PCB zip codes was on average...
- Low birth weight linked to long-term respiratory problems.(Report)
- Newspaper article from: Pediatrics Week July 25, 2009 700+ words
...in young adults with a history of low birth weight," wrote lead researcher Eric C. Walter...findings suggest that not only are [low birth weight] survivors at increased risk for long...diagnoses. They then linked these cases to birth weight data listed on birth certificates where...
- Low birth weight and interactions between traditional risk factors.
- Journal of Genetic Psychology Abel, Millicent H. December 1, 1997 700+ words
Low birth weight, defined as a birth weight of less than 2,500 g, is one of several perinatal risk...studies, the Institute of Medicine (1985) emphasized low birth weight as a major determinant of infant mortality. Low birth weight...
- Disadvantages from very low birth weight last into young adulthood....
- Magazine article from: Perspectives on Sexual and Reproductive Health Rosenberg, J. May 1, 2002 700+ words
Very-low-birth-weight individuals (those weighing less than 1,500...However, at age 20, women who were very-low-birth-weight are less likely than their normal-birth-weight peers to report having used alcohol or drugs...
- HENRY FORD HOSPITAL: IQ LINKED TO BIRTH WEIGHT
- Press release article from: PR Newswire April 28, 1994 700+ words
...DETROIT, April 28 /PRNewswire/ -- Birth weight is one determinant of IQ, concluded...Henry Ford Hospital researcher. Low birth weight has an adverse effect on children...Hospital. The study found that low birth weight children -- a birth weight of 2,500...
