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Structured diet nears statin for LDL lowering.(News)
NEW YORK -- Diet can work almost as well as a statin for cutting a patient's level of LDL cholesterol.
Patients who stuck with a highly structured diet rich in plant sterols, soy protein, viscous fibers, and almonds maintained their serum LDL-cholesterol level at 30% below their baseline level for a year, a decrease that was similar to the average 33% drop seen in patients treated with 20 mg of lovastatin daily, David J.A. Jenkins, M.D., reported at an international symposium on triglycerides and HDL cholesterol.
"Using cholesterol-lowering foods bridges the therapeutic gap between a generally good diet and statin therapy," said Dr. Jenkins, a professor in the department of nutritional sciences at the University of Toronto.
The special diet also dropped the average starting serum level of C-reactive protein by about 30%, compared with an average 35% reduction in the patients treated with lovastatin.
The year-long study began with a total of 66 patients with LDL-cholesterol levels of at least 158 mg/dL at baseline who had not taken statins for 2 weeks prior to the study and were otherwise healthy; 58 completed the full 52 weeks on treatment.
The diet tested by Dr. Jenkins and his associates was built on a foundation of the American Heart Association's step II diet, which is ...
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